Author: Staff Corvelva
These latest analyses were made possible thanks to the active contribution of the French associations Association Liberté Informations Santé (ALIS), Ligue nationale pour la liberté des vaccinations (LNPLV) and the Australian Association Australian Vaccination-risks Network (AVN), that we thank.
New generation sequencing have become the preferred tool for in-depth analysis in the field of biology and medical science, especially high precision ones. Thanks to these tools, we can approach in a more modern and comprehensive way a number of applications such as de novo sequencing, metagenomic and epigenomic studies, transcriptome sequencing and genome re-sequencing.
This last one (re-sequencing) is largely used in human field, both for research and diagnostic purposes and consists of NGS - Next Generation Sequencing of an entire single genome, to map the Single Nucleotide mutations (SNP), insertions and deletions of more or less long sequences that have occurred in certain locations of the genome, and variations in the number of copies of genomic portions/genes (CNV, Copy Number Variants).
This procedure helps to understand the development mechanism of some pathologies, in order to identify the directions for a future clinical treatment as in the case of cancer for example. Indeed, by this method the genetic heritage of a cancer patient can be fully decoded in both normal and cancerous tissue, thus allowing us to comprehend what exactly has changed within the genome, and, if possible, how to intervene with targeted measures.
The re-sequencing procedure requires that the DNA of an individual is mechanically broken into small dimension fragments (400-500 base pairs) and artificial DNA parts named adapters are tied to these fragments; adapters make it possible to tie the human DNA fragments to a glass surface on which the bases reading (A, C, G, T) is performed. The DNA base pairs reading takes place by means of chemical reactions, namely the incorporation of nucleotides that have been marked by fluorescent molecules. The million sequences (reads) thus obtained are then mapped on the human reference genome by specific software and all the variants are identified comparing the analyzed genome with the reference genome.
This same procedure has been performed on the human genome in Priorix® Tetra lot n. A71CB256A, genome which belongs to cell line MRC-5 (of fetal origin); the work has been carried out by a company in the USA, that routinely deals with human genome re-sequencing analysis. *
*the name of the laboratory that has performed the analysis will be included in the next formal complaint we will file at the Public Prosecutor of Rome and as well at the Italian and European regulatory bodies. The associations who are filing the analysis funded by Corvelva will be promptly kept up to date with these shocking results too. We are no denying that we feel, especially as parents, distressed by these results we are reporting - as if what we have found out so far was not enough to worry about.
Author: Paul Joseph Watson
“How can this be allowed”.
Budget airline EasyJet was on the defensive this morning after a passenger posted an image of a woman being forced to sit in a ‘backless seat’ on the aircraft.
“#easyjet beats @Ryanair to have backless seats. @IATA @EASA this is flight 2021 Luton to Geneva. How can this be allowed,” tweeted Matthew Harris.
The White House is circulating drafts of a proposed executive order that would address allegations of anti-conservative bias by social media companies, according to a White House official and two other people familiar with the matter — a month after President Donald Trump pledged to explore "all regulatory and legislative solutions" on the issue.
None of the three would describe the contents of the order, which one person cautioned has already taken many different forms and remains in flux. But its existence, and the deliberations surrounding it, are evidence that the administration is taking a serious look at wielding the federal government’s power against Silicon Valley.
“If the internet is going to be presented as this egalitarian platform and most of Twitter is liberal cesspools of venom, then at least the president wants some fairness in the system,” the White House official said. “But look, we also think that social media plays a vital role. They have a vital role and an increasing responsibility to the culture that has helped make them so profitable and so prominent."
Author: Alexa St. John
Business owners and leaders say labor costs have forced cuts in jobs and work shifts.
More than six months after the $15 minimum wage went into effect in New York City, business leaders and owners say the increased labor costs have forced them to cut staff, eliminate work shifts and raise prices.
Many business owners said these changes were unintended consequences of the new minimum wage, which took effect at the beginning of the year.
Author: Thomas M. Burton
U.S. agency ‘remains confident’ that Zolgensma, used to treat an infant muscle-wasting disease, should stay on market.
WASHINGTON—The Food and Drug Administration said “data manipulation” took place during company studies of Zolgensma, the world’s most expensive drug, but officials said the gene therapy product still should stay on the market.
The medicine, which costs in the range of $2.1 million for a one-time infusion, treats children with an especially devastating, sometimes fatal form of spinal muscular atrophy. The FDA said it was informed after the May 24 approval of the drug that there had been a data-manipulation issue. That information came from AveXis Inc. of Bannockburn, Ill., the product’s maker and a unit of Novartis AG.
Author: Fred Imbert
Stock futures tumbled on Monday night, adding to Wall Street’s losses from its worst day of 2019 amid intensifying trade-war fears.
Dow Jones Industrial Average futures traded 508 points lower, implying a loss of 630.74 points at Tuesday’s open. S&P 500 and Nasdaq 100 futures also indicated sharp losses. If these losses remain, the Dow’s two-day decline would amount to more than 1,300 points.
Author: Rachel Koning Beals
Haven metal benefits as dollar eases, yields retreat and stocks sink in wake of China-U.S. trade tensions.
Gold’s haven appeal boosted the metal to a more than six-year high on Monday, as an escalating U.S.-China trade fight sparked a selloff in assets perceived as risky.
Gold, now up about 15% from its low of 2019, has surged over recent sessions after President Donald Trump intensified a trade fight with China by announcing additional tariffs on Chinese goods and China pledged retaliation.
Author: Sofie Jackson
SCIENTISTS battling to build the first supercomputer with human-level intelligence think size could be the key to the Holy Grail of AI breakthroughs.
Microsoft has recently injected $1 billion into an artificial intelligence research group co-founded by tech genius Elon Musk which is aiming to be the first to build a computer which matches its creators for intelligence.
The group, OpenAI, even thinks such a milestone could happen inside five years.
Author: Eileen Brown
There is nothing wrong with bonding over a beer or two after work, but when it becomes too much, it is important to spot the warning signs of substance abuse and addiction, according to a new study.
Across all professional fields in the US, substance addiction can affect anyone, but are specific industries more at risk than others?
Author: Sharon Terlep
Technology lets companies see how badly they can treat consumers, right up until the moment they bolt.
In corporate parlance, it’s called the “breakpoint.” It’s how far customers can be pushed before their heads explode.
From long waits at the airport to rude store clerks to ineffective helplines, shoddy customer service is a universal frustration. Today, companies crunch data and use artificial intelligence to determine exactly how angry a customer has to be to bolt. Many are walking right up to that line.